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Craig A. Branch, Ph.D.

Associate Professor, Radiology

Director, Gruss Magnetic Resonance Research Center

Co-Director, EGL Integrated Imaging Program

Magnetic resonance imaging (MRI)Sickle cell disease Traumatic Brain Injury and Concussion MRI measures of function and physiology

Dr. Craig Branch is an internationally-known MRI researcher who has been a pioneer in using the technology since it was first developed in the early 1980s. Dr. Branch directs Einstein’s Gruss Magnetic Resonance Research Center, which supports a wide variety of MRI studies of brain injury and disease, liver disease, cancer, and other disorders.

Dr. Branch specializes in the use of MRI to study disease in both humans and animal models. He was one of the first to use MRI to measure blood flow in the brain, and he employs the technology to assess brain function and structure in numerous disorders, including sickle cell disease, stroke, traumatic brain injury and schizophrenia. He is one of the only researchers to have used animal models of sickle cell disease (SCD) to research the biological mechanisms that underlie cognitive impairment and strokes in SCD. Research findings in this area suggest that brain blood flow associated with SCD strokes is unusually high—a finding that could lead to treatments that might ward off strokes in SCD patients.

Dr. Branch is also Co-Director of the Evelyn-Gruss-Lipper Integrated Imaging Program (EGL-IIP) which seeks to use microscopic-to-macroscopic imaging scales to understand the mechanisms that contribute to breast and other metastatic cancers. Research in this area incorporates both rodent models of cancer and clinical studies of human breast cancer. In addition to his NIH-funded research, Dr. Branch has served as an MRI expert on several NIH ad-hoc review committees.

John S. Condeelis, Ph.D.

Professor, Cell Biology

The Judith and Burton P. Resnick Chair in Translational Research

Chair Emeritus Department of Anatomy & Structural Biology

Co-Director, Integrated Imaging Program

Scientific Director, Analytical Imaging Facility

Director, Integrated Imaging Program for Cancer Research

Biomedical technologiesIntravital imagingTumor microenvironmentBreast cancerMetastasis

Dr. Condeelis is a pioneer in developing microscope techniques for use in “intravital imaging” – observing the behavior of cells in living animals. His work has led to a clinical test of biopsy tissue to determine whether a woman’s breast cancer will spread (metastasize), which could help determine treatment. Because of the test’s success, Dr. Condeelis and colleagues have licensed the patent rights to a biotech firm, which is developing the tissue test into a commercial product. read more...

John M. Greally, Ph.D., D.Med., M.B.,B.Ch.,B.A.O.

Director, Center for Epigenomics, Einstein

Faculty Scholar for Epigenomics, Einstein

Attending Physician, Pediatrics, The Children's Hospital at Montefiore

GeneticsEpigenetics/epigenomics

Dr. Greally began his career as a pediatrician who subspecialized in clinical genetics, seeing patients with genetic syndromes, birth defects and developmental problems. Now, Dr. Greally seeks to understand how genetic disease is caused not by DNA mutations, but due to abnormalities in how genes are switched off and on – a field known as epigenomics. read more...

Jeffrey E. Segall, Ph.D.

Professor, Anatomy and Structural Biology

Professor, Pathology

Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research

Biomedical technologiesImagingTumor cell imaging

Dr. Segall studies how tumor cells invade tissues and spread through the body. He has developed sophisticated imaging methods for following individual tumor cells moving in living animals. For example, one of his techniques involves a tiny glass window implanted in the skin of a mouse that allows scientists to track individual cancer cells as they spread a tumor site and attack other parts of the body. This technique could one day be used for assessing the effectiveness of specific drugs in preventing cancer from metastasizing. read more...